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Biomarkers for the lung cancer diagnosis and their advances in proteomics

Published on Sep 30, 2008in Journal of Biochemistry and Molecular Biology
· DOI :10.5483/BMBRep.2008.41.9.615
Hye-Jin Sung5
Estimated H-index: 5
,
Je-Yoel Cho28
Estimated H-index: 28
(KNU: Kyungpook National University)
Abstract
Over a last decade, intense interest has been focused on bio-marker discovery and their clinical uses. This interest is accel-erated by the completion of human genome project and the progress of techniques in proteomics. Especially, cancer bio-marker discovery is eminent in this field due to its anticipated critical role in early diagnosis, therapy guidance, and prognosis monitoring of cancers. Among cancers, lung cancer, one of the top three major cancers, is the one showing the highest mortal-ity because of failure in early diagnosis. Numerous potential DNA biomarkers such as hypermethylations of the promoters and mutations in K-
  • References (112)
  • Citations (113)
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Last.Paul S. Thomas (UNSW: University of New South Wales)H-Index: 40
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#1Sun-Hee Heo (KNU: Kyungpook National University)H-Index: 8
#2Seung-Jin Lee (KNU: Kyungpook National University)H-Index: 13
Last.Je-Yoel Cho (KNU: Kyungpook National University)H-Index: 28
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Cited By113
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#1Xuanyu Wang (DUT: Dalian University of Technology)
#2Yongjun Shang (DUT: Dalian University of Technology)
Last.Shuangping Liu (DUT: Dalian University of Technology)
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#1Dan Xiong (Fudan University)
#2Yunlin Ye (SYSU: Sun Yat-sen University)
Last.Jiehong Wei (SZU: Shenzhen University)
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#1Chang Liu (JLU: Jilin University)H-Index: 15
#2Fanling Meng (JLU: Jilin University)H-Index: 1
Last.Xiaoqiang Cui (JLU: Jilin University)H-Index: 18
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#1Yu Liu (Hunan Institute of Science and Technology)H-Index: 1
#2Xiaohong Xun (Hunan Institute of Science and Technology)H-Index: 2
Last.Jie Hua (Hunan Institute of Science and Technology)H-Index: 1
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View next paperBiomarkers for lung cancer: clinical uses