Original paper
Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation
Abstract
The transcription factor p63 plays a pivotal role in keratinocyte proliferation and differentiation in the epidermis. However, how p63 regulates epidermal genes during differentiation is not yet clear. Using epigenome profiling of differentiating human primary epidermal keratinocytes, we characterized a catalog of dynamically regulated genes and p63-bound regulatory elements that are relevant for epithelial development and related diseases....
Paper Details
Title
Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation
Published Date
Jun 1, 2015
Journal
Volume
16
Issue
7
Pages
863 - 878
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Notes
History