The effect of phosphorylation on arrestin-rhodopsin interaction in the squid visual system
Abstract
Invertebrate visual opsins are G protein-coupled receptors coupled to retinoid chromophores that isomerize reversibly between inactive rhodopsin and active metarhodopsin upon absorption of photons of light. The squid visual system has an arrestin protein that binds to metarhodopsin to block signaling to Gq and activation of phospholipase C. Squid rhodopsin kinase (SQRK) can phosphorylate both metarhodopsin and arrestin, a dual role that is...
Paper Details
Title
The effect of phosphorylation on arrestin-rhodopsin interaction in the squid visual system
Published Date
Oct 28, 2015
Journal
Volume
135
Issue
6
Pages
1129 - 1139
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