CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases
Abstract
Animal models are extremely valuable to help us understand the pathogenesis of neurodegenerative disorders and to find treatments for them. Since large animals are more like humans than rodents, they make good models to identify the important pathological events that may be seen in humans but not in small animals; large animals are also very important for validating effective treatments or confirming therapeutic targets. Due to the lack of...
Paper Details
Title
CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases
Published Date
Aug 4, 2015
Journal
Volume
10
Issue
1
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