Impact of in‐patient research participation on subsequent heroin use patterns: implications for ethics and public health

Aims Research on drug dependence often involves the administration of drugs of abuse to experienced drug users under controlled laboratory conditions. The primary objective of this study was to assess whether participation in such research alters the frequency of heroin use by non‐treatment‐seeking opioid‐dependent volunteers after study completion. Design Data were examined from four in‐patient studies involving controlled opioid...