Systemic mastocytosis in adults: 2013 update on diagnosis, risk stratification, and management
Abstract
Disease overview : Systemic mastocytosis (SM) results from a clonal proliferation of abnormal mast cells (MC) in one or more extracutaneous organs. Diagnosis : The major criterion is presence of multifocal clusters of morphologically abnormal MC in the bone marrow. Minor diagnostic criteria include elevated serum tryptase level, abnormal MC expression of CD25 and/or CD2, and presence of KIT D816V. Risk stratification : The 2008 World Health...
Paper Details
Title
Systemic mastocytosis in adults: 2013 update on diagnosis, risk stratification, and management
Published Date
May 30, 2013
Volume
88
Issue
7
Pages
612 - 624
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