Selection of solid-state excipients for simvastatin dosage forms through thermal and nonthermal techniques
Volume: 121, Issue: 3, Pages: 1093 - 1102
Published: Jun 25, 2015
Abstract
The importance of developing new pharmaceutical final formulations is nowadays well known. In this paper, we present the study of compatibility between bioactive antihyperlipidemic agent simvastatin and eight currently used pharmaceutical excipients for developing solid dosage forms, namely starch, microcrystalline cellulose, lactose monohydrate, polyvinylpyrrolidone, colloidal silica, talc, magnesium citrate and sorbitol. The compatibility...
Paper Details
Title
Selection of solid-state excipients for simvastatin dosage forms through thermal and nonthermal techniques
Published Date
Jun 25, 2015
Volume
121
Issue
3
Pages
1093 - 1102
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