A Novel Model for IFN-γ–Mediated Autoinflammatory Syndromes
Abstract
Autoinflammatory disease and hyperinflammatory syndromes represent a growing number of diseases associated with inappropriately controlled inflammation in multiple organs. Systemic inflammation commonly results from dysregulated activation of innate immune cells, and therapeutic targeting of the IL-1β pathway has been used to ameliorate some of these diseases. Some hyperinflammatory syndromes, however, such as hemophagocytic lymphohistiocytosis...
Paper Details
Title
A Novel Model for IFN-γ–Mediated Autoinflammatory Syndromes
Published Date
Mar 1, 2015
Journal
Volume
194
Issue
5
Pages
2358 - 2368
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Notes
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