Meal modulation of circulating interleukin 18 and adiponectin concentrations in healthy subjects and in patients with type 2 diabetes mellitus

Background: A single high-fat meal induces endothelial activation, which is associated with increased serum concentrations of inflammatory cytokines. Objective: We compared the effect of 3 different meals on circulating concentrations of interleukin 8 (IL-8), interleukin 18 (IL-18), and adiponectin in healthy subjects and in patients with type 2 diabetes mellitus. Design: Thirty patients with newly diagnosed type 2 diabetes and 30 matched,...