Systemic mastocytosis in adults: 2012 Update on diagnosis, risk stratification, and management
Abstract
Systemic mastocytosis (SM) results from a clonal proliferation of abnormal mast cells (MC) in one or more extra-cutaneous organs.The major criterion is presence of multifocal clusters of morphologically abnormal MC in the bone marrow. Minor diagnostic criteria include elevated serum tryptase level, abnormal MC expression of CD25 and/or CD2, and presence of KITD816V.The prognostic relevance of the 2008 World Health Organization (WHO)...
Paper Details
Title
Systemic mastocytosis in adults: 2012 Update on diagnosis, risk stratification, and management
Published Date
Mar 13, 2012
Volume
87
Issue
4
Pages
401 - 411
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