Characterization of diabetic osteoarthritic cartilage and role of high glucose environment on chondrocyte activation: toward pathophysiological delineation of diabetes mellitus-related osteoarthritis

Volume: 23, Issue: 9, Pages: 1513 - 1522
Published: Sep 1, 2015
Abstract
Summary null Objective null To examine the relationship between osteoarthritis (OA) and type 2 diabetes mellitus (DM). null Methods null OA cartilage from DM and non-DM patients undergoing knee replacement were stimulated by IL-1β for 24 h and release of interleukin-6 (IL-6) and prostaglandin E 2 null (PGE 2 ) was measured. Primary cultured murine chondrocytes were stimulated for 24 and 72 h with or without IL-1β (5 ng/mL) under normal-glucose...
Paper Details
Title
Characterization of diabetic osteoarthritic cartilage and role of high glucose environment on chondrocyte activation: toward pathophysiological delineation of diabetes mellitus-related osteoarthritis
Published Date
Sep 1, 2015
Volume
23
Issue
9
Pages
1513 - 1522
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