Effective intra‐S checkpoint responses to UVC in primary human melanocytes and melanoma cell lines
Abstract
The objective of this study was to assess potential functional attenuation or inactivation of the intra-S checkpoint during melanoma development. Proliferating cultures of skin melanocytes, fibroblasts, and melanoma cell lines were exposed to increasing fluences of UVC and intra-S checkpoint responses were quantified. Melanocytes displayed stereotypic intra-S checkpoint responses to UVC qualitatively and quantitatively equivalent to those...
Paper Details
Title
Effective intra‐S checkpoint responses to UVC in primary human melanocytes and melanoma cell lines
Published Date
Nov 3, 2015
Volume
29
Issue
1
Pages
68 - 80
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