S-adenosyl methionine (SAMe) for depression in adults

Depression is a recurrent illness with high rates of chronicity, treatment-resistance and significant economic impact. There is evidence in the literature that S-adenosyl methionine (SAMe), a naturally occurring compound in the human body, has antidepressant efficacy. This product may be an important addition to the armamentarium of antidepressant agents.To assess the effects of SAMe in comparison with placebo or antidepressants for the...