Retinoic acid receptor β2 agonists restore glycaemic control in diabetes and reduce steatosis
Abstract
To investigate the effects of specific retinoic acid receptor (RAR) agonists in diabetes and fatty liver disease.Synthetic agonists for RARβ2 were administered to wild-type (wt) mice in a model of high-fat-diet (HFD)-induced type 2 diabetes (T2D) and to ob/ob and db/db mice (genetic models of obesity-associated T2D).We show that administration of synthetic agonists for RARβ2 to either wt mice in a model of HFD-induced T2D or to ob/ob and db/db...
Paper Details
Title
Retinoic acid receptor β2 agonists restore glycaemic control in diabetes and reduce steatosis
Published Date
Dec 23, 2015
Volume
18
Issue
2
Pages
142 - 151
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