c-JunN-terminal kinase inhibitors: a patent review (2010 – 2014)

Volume: 25, Issue: 8, Pages: 849 - 872
Published: May 19, 2015
Abstract
c-Jun N-terminal kinases (JNKs) are involved in the emergence and progression of diverse pathologies such as neurodegenerative, cardiovascular and metabolic disorders as well as inflammation and cancer. In recent years, several highly selective pan-JNK inhibitors have been characterized and three chemical entities targeting JNKs have been investigated in clinical trials.This review summarizes patents claiming inhibitors of all JNK isoforms...
Paper Details
Title
c-JunN-terminal kinase inhibitors: a patent review (2010 – 2014)
Published Date
May 19, 2015
Volume
25
Issue
8
Pages
849 - 872
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