Human and murine APOBEC3s restrict replication of koala retrovirus by different mechanisms
Abstract
Koala retrovirus (KoRV) is an endogenous and exogenous retrovirus of koalas that may cause lymphoma. As for many other gammaretroviruses, the KoRV genome can potentially encode an alternate form of Gag protein, glyco-gag. In this study, a convenient assay for assessing KoRV infectivity in vitro was employed: the use of DERSE cells (initially developed to search for infectious xenotropic murine leukemia-like viruses). Using infection of DERSE and...
Paper Details
Title
Human and murine APOBEC3s restrict replication of koala retrovirus by different mechanisms
Published Date
Aug 8, 2015
Journal
Volume
12
Issue
1
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