The Adverse Effects of Comorbid Pain on Depression Outcomes in Primary Care Patients: Results from the Artist Trial

To explore the effect of pain symptoms and improvements in pain on depression outcomes.We analyzed data from A Randomized Trial Investigating SSRI Treatment (ARTIST), a randomized longitudinal effectiveness study comparing selective serotonin reuptake inhibitors (SSRIs) for the treatment of depression in primary care (n = 573). Depression outcome at month 6, defined as remission, partial response, and nonresponse using the Symptom Checklist-20,...