Experimental Induction of Hangover

The literature (55 references) on the symptomatology, pathophysiological mechanisms and the possible role of congeners in the etiology of hangover is briefly discussed. In experimental party settings 91 moderate drinkers (in groups of 4 to 10), aged 21 to 35, of both sexes, drank 1 to 1.75 ml of alcohol per kg as bourbon, or vodka diluted with water. The amount of food and drink taken prior to, during and after alcohol ingestion and dilution and...