Thrombomodulin: protectorate God of the vasculature in thrombosis and inflammation

SummaryThrombomodulin (TM) is an endothelial anticoagulant cofactor that promotes thrombin‐mediated activation of protein C. Recently, we conducted a multicentre, double‐blind, randomized trial to evaluate the efficacy and safety of recombinant human soluble thrombomodulin (rhsTM, also known as ART‐123) for the treatment of disseminated intravascular coagulation (DIC), and found that rhsTM therapy is more effective and safer than low‐dose...