Are Obesity-Related Insulin Resistance and Type 2 Diabetes Autoimmune Diseases?
Abstract
Obesity and associated insulin resistance predispose individuals to develop chronic metabolic diseases, such as type 2 diabetes and cardiovascular disease. Although these disorders affect a significant proportion of the global population, the underlying mechanisms of disease remain poorly understood. The discovery of elevated tumor necrosis factor-α in adipose tissue as an inducer of obesity-associated insulin resistance marked a new era of...
Paper Details
Title
Are Obesity-Related Insulin Resistance and Type 2 Diabetes Autoimmune Diseases?
Published Date
May 16, 2015
Journal
Volume
64
Issue
6
Pages
1886 - 1897
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Notes
History