Digit tip regeneration correlates with regions of Msx1 (Hox 7) expression in fetal and newborn mice
Abstract
We report that during mouse fetal development transcripts of Msx1 and Msx2 become progressively restricted to cells that will form more distal digit structures; the Msx2 expression domain is always more distal than Msx1. At birth both Msx1 and Msx2 are expressed in cells of the nail bed and hair follicle. We have found that the regenerative ability of mouse digit tips is restricted to levels in which the amputation plane is within the region of...
Paper Details
Title
Digit tip regeneration correlates with regions of Msx1 (Hox 7) expression in fetal and newborn mice
Published Date
Apr 1, 1995
Journal
Volume
121
Issue
4
Pages
1065 - 1076
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