The α7 nicotinic acetylcholine receptor function in hippocampal neurons is regulated by the lipid composition of the plasma membrane

Volume: 589, Issue: 13, Pages: 3163 - 3174
Published: Jun 29, 2011
Abstract
Non‐technical summary The α7 nicotinic acetylcholine receptors (nAChRs) are a therapeutic target for the treatment of neurological disorders such as Alzheimer's disease and schizophrenia, and drugs that potentiate α7 nAChRs through the regulation of desensitization are currently being developed. Here we show that changes to the lipid composition of the plasma membrane in rat hippocampal neurons, through either acute treatment with drugs that...
Paper Details
Title
The α7 nicotinic acetylcholine receptor function in hippocampal neurons is regulated by the lipid composition of the plasma membrane
Published Date
Jun 29, 2011
Volume
589
Issue
13
Pages
3163 - 3174
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