Recognition of nucleic acids by pattern‐recognition receptors and its relevance in autoimmunity
Abstract
Summary: Host cells trigger signals for innate immune responses upon recognition of conserved structures in microbial pathogens. Nucleic acids, which are critical components for inheriting genetic information in all species including pathogens, are key structures sensed by the innate immune system. The corresponding receptors for foreign nucleic acids include members of Toll‐like receptors, RIG‐I‐like receptors, and intracellular DNA sensors....
Paper Details
Title
Recognition of nucleic acids by pattern‐recognition receptors and its relevance in autoimmunity
Published Date
Aug 26, 2011
Journal
Volume
243
Issue
1
Pages
61 - 73
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Notes
History