Nucleocapsid Protein: A Desirable Target for Future Therapies Against HIV-1
Abstract
The currently available anti-HIV-1 therapeutics is highly beneficial to infected patients. However, clinical failures occur as a result of the ability of HIV-1 to rapidly mutate. One approach to overcome drug resistance is to target HIV-1 proteins that are highly conserved among phylogenetically distant viral strains and currently not targeted by available therapies. In this respect, the nucleocapsid (NC) protein, a zinc finger protein, is...
Paper Details
Title
Nucleocapsid Protein: A Desirable Target for Future Therapies Against HIV-1
Published Date
Jan 1, 2015
Journal
Pages
53 - 92
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