Polyphyllin I induced-apoptosis is enhanced by inhibition of autophagy in human hepatocellular carcinoma cells
Abstract
Polyphyllin I (PPI), a bioactive phytochemical isolated from the rhizoma of Paris polyphyllin, exerts preclinical anticancer efficacy in various cancer models. However, the effects of PPI on regulatory human hepatocellular carcinoma (HCC) cell proliferation and its underlying mechanisms remain unknown.This study investigated the antiproliferation effect of PPI on HCC cells and its underlying mechanisms.Cell viability was measured by MTT assay....
Paper Details
Title
Polyphyllin I induced-apoptosis is enhanced by inhibition of autophagy in human hepatocellular carcinoma cells
Published Date
Dec 1, 2015
Journal
Volume
22
Issue
13
Pages
1139 - 1149
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