Continuous tank reactor synthesis of highly substituted sulphobutylether β-cyclodextrins

Volume: 495, Issue: 2, Pages: 862 - 868
Published: Nov 30, 2015
Abstract
Batch synthesis of sulphobutyl ether β-cyclodextrin (also known as SBE-β-CD or SBECD) is a process effectively divided into three main stages, i.e. initial reagent dissolution, a sulphoalkylation reaction and final reaction quenching. This reaction is followed by downstream processing and purification, and ultimate isolation of the solid SBECD material. However, a feature associated with using this synthetic method is that a high proportion of...
Paper Details
Title
Continuous tank reactor synthesis of highly substituted sulphobutylether β-cyclodextrins
Published Date
Nov 30, 2015
Volume
495
Issue
2
Pages
862 - 868
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