Synthesis, antiviral, cytotoxicity and antitumor evaluations of A4 type of porphyrin derivatives

Volume: 19, Issue: 06, Pages: 753 - 768
Published: Jun 1, 2015
Abstract
This manuscript describes the synthesis of a new series of porphyrin structures 4a–4m, 7, 9, 12 and 14. These structures were investigated against two types of viruses such as HIV-1 and HSV-1. Also they were screened for their antitumor activity. Among all tested compounds, it was found that compound 4b showed a high activity against HIV-1 and HSV-1 and against four different tumor cell lines. Most of the tested compounds showed a moderate...
Paper Details
Title
Synthesis, antiviral, cytotoxicity and antitumor evaluations of A4 type of porphyrin derivatives
Published Date
Jun 1, 2015
Volume
19
Issue
06
Pages
753 - 768
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