Original paper

Characterization of protein adsorption onto silica nanoparticles: influence of pH and ionic strength

Volume: 293, Issue: 11, Pages: 3381 - 3391
Published: Sep 11, 2015
Abstract
The adsorption of lysozyme and ß-lactoglobulin onto silica nanoparticles (diameter 21 nm) was studied in the pH range 2-11 at three different ionic strengths. Since the two proteins have a widely different isoelectric point (pI), electrostatic interactions with the negative silica surface lead to a different dependence of adsorption on pH. For lysozyme (pI ≈ 11), the adsorption level increases with pH and reaches a value corresponding to about...
Paper Details
Title
Characterization of protein adsorption onto silica nanoparticles: influence of pH and ionic strength
Published Date
Sep 11, 2015
Volume
293
Issue
11
Pages
3381 - 3391
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