CXCL13 mediates prostate cancer cell proliferation through JNK signalling and invasion through ERK activation
Abstract
The focus of this study was to determine the dedicator of cytokinesis 2 (DOCK2), extracellular signal-regulated kinase 1/2 (ERK1/2), c-Jun N-terminal kinase-1 (JNK) and Akt signals involved in CXCL13-mediated prostate cancer (PCa) cell invasion and proliferation. Androgen-sensitive (LNCaP), hormone-refractory (PC3) cells and normal cells (RWPE-1) were used to determine CXCL13-mediated PCa cell invasion and proliferation. Immuno-blotting, fast...
Paper Details
Title
CXCL13 mediates prostate cancer cell proliferation through JNK signalling and invasion through ERK activation
Published Date
Jun 6, 2011
Journal
Volume
44
Issue
4
Pages
311 - 319
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