The In Vivo Pericapsular Tissue Response to Modern Polyurethane Breast Implants

Polyurethane breast implants were first introduced by Ashley (Plast Reconstr Surg 45:421–424, 1970), with the intention of trying to reduce the high incidence of capsular contracture associated with smooth shelled, high gel bleed, silicone breast implants. The sterilization of the polyurethane foam in the early days was questionable. More recently, ethylene oxide (ETO)-sterilized polyurethane has been used in the manufacturing process and this...