Nitric oxide and energy metabolism in mammals

Volume: 39, Issue: 4, Pages: 383 - 391
Published: Jul 1, 2013
Abstract
Nitric oxide (NO) is a signaling molecule synthesized from L-arginine by NO synthase in animals. Increasing evidence shows that NO regulates the mammalian metabolism of energy substrates and that these effects of NO critically depend on its concentrations at the reaction site and the period of exposure. High concentrations of NO (in the micromolar range) irreversibly inhibit complexes I, II, III, IV, and V in the mitochondrial respiratory chain,...
Paper Details
Title
Nitric oxide and energy metabolism in mammals
Published Date
Jul 1, 2013
Journal
Volume
39
Issue
4
Pages
383 - 391
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