Elevated alanine aminotransferase in antiretroviral-naïve HIV-infected African patients: magnitude and risk factors

Background Alanine aminotransferase ( ALT ) is commonly used to measure liver injury in resource‐limited settings. Elevations in ALT are predictive of increased mortality from liver disease and may influence the choice of first‐line antiretroviral therapy ( ART ). Methods A cross‐sectional analysis of the prevalence and predictors of elevated ALT (defined as > 40 IU / L ) was conducted. ART ‐naïve, HIV ‐infected adults with a baseline ALT...