Kallikrein-related peptidase 5 induces miRNA-mediated anti-oncogenic pathways in breast cancer

Volume: 1, Issue: 11, Pages: 709 - 724
Published: Oct 24, 2014
Abstract
Kallikrein-related peptidase 5 (KLK5) displays aberrant expression in cancer. Recently, we showed KLK5 reconstitution in breast cancer cell lines suppresses malignancy. Present study aims to investigate the functional KLK5 mediated miRNA network on breast cancer progression, molecular subtype and survival. 28 miRNAs were up-regulated and 62 miRNAs were down-regulated upon KLK5 expression. Extracellular matrix (ECM) molecules and cell-adhesion...
Paper Details
Title
Kallikrein-related peptidase 5 induces miRNA-mediated anti-oncogenic pathways in breast cancer
Published Date
Oct 24, 2014
Volume
1
Issue
11
Pages
709 - 724
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