Spatial sexual dimorphism of X and Y homolog gene expression in the human central nervous system during early male development
Abstract
Renewed attention has been directed to the functions of the Y chromosome in the central nervous system during early human male development, due to the recent proposed involvement in neurodevelopmental diseases. PCDH11Y and NLGN4Y are of special interest because they belong to gene families involved in cell fate determination and formation of dendrites and axon.We used RNA sequencing, immunocytochemistry and a padlock probing and rolling circle...
Paper Details
Title
Spatial sexual dimorphism of X and Y homolog gene expression in the human central nervous system during early male development
Published Date
Jan 12, 2016
Journal
Volume
7
Issue
1
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