Detailed Analysis of Protein Crystallization and Aggregation Phenomena Applying Dynamic Light Scattering

Obtaining X-ray suitable crystals is to date the rate limiting step to solve the structure of biological macromolecules such as proteins at atomic resolution. Those Structures are required for the design of novel drugs and to understand the way biological systems work. Rationalization of crystallization by biophysical methods is a promising way to accelerate this process. Here Dynamic Light Scattering (DLS) was applied in order to develop novel...