Ex vivo addition of fibrinogen concentrate improves the fibrin network structure in plasma samples taken during liver transplantation

Volume: 13, Issue: 12, Pages: 2192 - 2201
Published: Nov 20, 2015
Abstract
Optimal hemostatic management during orthotopic liver transplantation (OLT) remains a challenge. The cause of bleeding during OLT is multifactorial, and may include hemostatic imbalance. Fibrinogen concentrates are increasingly being used to control perioperative bleeding during OLT. However, administration is based on arbitrary thresholds of fibrinogen levels. Importantly, studies on fibrin clot structure during OLT are lacking.We determined...
Paper Details
Title
Ex vivo addition of fibrinogen concentrate improves the fibrin network structure in plasma samples taken during liver transplantation
Published Date
Nov 20, 2015
Volume
13
Issue
12
Pages
2192 - 2201
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