Volume: 76, Issue: 1, Pages: 74 - 75
Published: Nov 1, 2015
Abstract
ISG15 is an interferon (IFN)-α/β-inducible protein that exists as a free molecule and conjugated to target proteins (ISGylation). In vivo studies in mice have demonstrated a critical role for ISG15 in antiviral immunity. By contrast, in humans, ISG15 has been shown to have critical functions, but not in antiviral immunity. Extracellular ISG15 is essential in IFN-γ-dependent antimycobacterial immunity, and intracellular ISG15 is essential for the...
Paper Details
Title
ID: 55
Published Date
Nov 1, 2015
Journal
Volume
76
Issue
1
Pages
74 - 75
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