Abstract 3881: A distinct DNA methylation signature defines breast cancer stem cells and predict cancer outcome
Abstract
Pluripotency of stem cells depends on epigenetic programs that regulate self-renewal and differentiation. During oncogenesis, dysregulation of these two programs leads to the development of cancer stem cells (CSCs). Recent evidence suggests that CSCs are relatively resistant to conventional therapies and responsible for metastasis formation. Deciphering these processes will help gain insight into oncogenesis and allow the development of new...
Paper Details
Title
Abstract 3881: A distinct DNA methylation signature defines breast cancer stem cells and predict cancer outcome
Published Date
Oct 1, 2014
Journal
Volume
74
Issue
19_Supplement
Pages
3881 - 3881
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