STING-Mediated DNA Sensing Promotes Antitumor and Autoimmune Responses to Dying Cells
Abstract
Adaptive immune responses to Ags released by dying cells play a critical role in the development of autoimmunity, allograft rejection, and spontaneous as well as therapy-induced tumor rejection. Although cell death in these situations is considered sterile, various reports have implicated type I IFNs as drivers of the ensuing adaptive immune response to cell-associated Ags. However, the mechanisms that underpin this type I IFN production are...
Paper Details
Title
STING-Mediated DNA Sensing Promotes Antitumor and Autoimmune Responses to Dying Cells
Published Date
Dec 15, 2014
Journal
Volume
193
Issue
12
Pages
6124 - 6134
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History