Actividad anticoagulante y Factor Xa símil del veneno del escorpión Tityus discrepans

Tityus discrepans null venom (TdV) produces a variety of haemostatic manifestations including alveoli fibrin deposition and/or prothrombin and partial thromboplastin time (PT, PTT) alterations in mammals. In vitro studies have demonstrated that TdV contains tissue plasminogen activator-like (t-PA), fibrinolytic and plasmin inhibitory compounds and produces platelets activation through GPVI and a novel Src-dependent signalling pathway. The aim of...