A recurrent D-strand association interface is observed in β-2 microglobulin oligomers

β‐2 microglobulin (β2m) is an amyloidogenic protein responsible for dialysis‐related amyloidosis in man. In the early stages of amyloid fibril formation, β2m associates into dimers and higher oligomers, although the structural details of such aggregates are poorly understood. To characterize the protein–protein interactions supporting the formation of oligomers, three individual β2m cysteine mutants and their disulfide‐linked homodimers (DIMC20,...