Clinicopathologic study of dextran sulfate sodium experimental murine colitis
Abstract
BACKGROUND: We undertook this study in order to fully characterize the clinical and histopathology features of the dextran sulfate sodium (DSS) model of experimental murine colitis and to discover the earliest histopathologic changes that lead to colitis. EXPERIMENTAL DESIGN: Acute colitis was induced in Swiss-Webster mice by 7 days of oral DSS with animals sacrificed daily. Chronic colitis was induced by: (a) 7 days of oral DSS followed by 7...
Paper Details
Title
Clinicopathologic study of dextran sulfate sodium experimental murine colitis
Published Date
Jan 1, 1998
Journal
Volume
69
Issue
2
Pages
238 - 249
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