BRAF mutation predicts for poor outcomes after metastasectomy in patients with metastatic colorectal cancer
Abstract
BRAF mutations occur in 5% to 11% of patients with metastatic colorectal cancer (mCRC) and have been associated with poor prognosis. The current study was undertaken to determine the clinicopathologic characteristics, PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha) mutation frequency, and outcomes after metastasectomy in patients with BRAF-mutant mCRC.Data from 1941 consecutive patients with mCRC who underwent...
Paper Details
Title
BRAF mutation predicts for poor outcomes after metastasectomy in patients with metastatic colorectal cancer
Published Date
Apr 15, 2014
Journal
Volume
120
Issue
15
Pages
2316 - 2324
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