Isolation and molecular characterization of a novel d‐hydantoinase from Jannaschia sp. CCS1

Hydantoinases (HYDs) are important enzymes for industrial production of optically pure amino acids, which are widely used as precursors for various semi‐synthetic antibiotics. By a process coupling genomic data mining with activity screening, a new hydantoinase, tentatively designated HYD Js , was identified from Jannaschia sp. CCS1 and overexpressed in Escherichia coli . The specific activity of HYD Js on d,l ‐ p‐ hydroxyphenylhydantoin as the...