Match!

Healthcare costs associated with osteoarthritis in US patients.

Published on Nov 1, 2012in Pain Practice2.49
· DOI :10.1111/j.1533-2500.2012.00535.x
T. Kim Le2
Estimated H-index: 2
(Eli Lilly and Company),
Lb Montejano7
Estimated H-index: 7
(Thomson Reuters)
+ 2 AuthorsDennis C. Ang20
Estimated H-index: 20
(IU: Indiana University)
Abstract
Background:  Osteoarthritis is a chronic debilitating condition affecting many adults in the United States. This study was to compare pharmacologic treatments and costs for newly diagnosed and existing osteoarthritis patients to assess unmet medication treatment needs and economic burden. Methods:  This retrospective analysis of de-identified medical and pharmacy insurance claims from the MarketScan® databases identified adult patients with an osteoarthritis claim in 2007. The date of the first osteoarthritis claim in 2007 served as the index. Patients were stratified into newly diagnosed and existing cohorts, based on the presence of osteoarthritis claim(s) over the 12-month pre-index period. Utilization of pain-related medications and healthcare costs was assessed in the 12-month postindex period. Multivariate analysis was conducted to adjust costs controlling for cross-cohort differences. Results:  Newly diagnosed osteoarthritis patients (n = 134,584) were younger (66.0 vs. 68.0, P < 0.001), had a higher proportion of men (37.4% vs. 33.9%, P < 0.001) but lower rates of comorbidities than existing patients (n = 123,653). Significantly higher proportions of newly diagnosed patients had an inpatient admission and outpatient office visit. Higher proportions of existing patients utilized a majority of the medication classes examined. Total adjusted osteoarthritis-related costs for newly diagnosed patients were 6,811 annually (95% confidence interval [CI] ,743 to 6,887), compared to ,407 (95% CI 6,327 to ,477) for existing patients. Costs of pain-related prescription drugs associated with osteoarthritis were 965 (95% CI 55 to 975) among new patients, less than the ,117 (95% CI 1,107 to ,129) among existing patients. Conclusion:  Newly diagnosed osteoarthritis patients incurred higher annual costs, but lower pain-related prescription drug costs in the year following diagnosis than patients with existing osteoarthritis.
  • References (13)
  • Citations (22)
References13
Newest
#1Joseph A. Zeni (UD: University of Delaware)H-Index: 21
#2Michael J. Axe (UD: University of Delaware)H-Index: 38
Last.Lynn Snyder-Mackler (UD: University of Delaware)H-Index: 70
view all 3 authors...
87 CitationsSource
84 Citations
#1H KotlarzH-Index: 3
#2Candace GunnarssonH-Index: 18
Last.John A. Rizzo (SBU: Stony Brook University)H-Index: 35
view all 4 authors...
260 CitationsSource
24 Citations
245 Citations
14 Citations
58 CitationsSource
#1Weiya Zhang (Edin.: University of Edinburgh)H-Index: 57
#2Roland W. Moskowitz (Edin.: University of Edinburgh)H-Index: 47
Last.Peter Tugwell (Edin.: University of Edinburgh)H-Index: 116
view all 16 authors...
1,870 CitationsSource
#1Reva C. LawrenceH-Index: 15
#2David T. Felson (BU: Boston University)H-Index: 137
Last.Frederick WolfeH-Index: 97
view all 14 authors...
3,603 CitationsSource
139 CitationsSource
Cited By22
Newest
#1Win Min Oo (RNSH: Royal North Shore Hospital)H-Index: 4
#2Shirley Pei-Chun Yu (RNSH: Royal North Shore Hospital)H-Index: 4
Last.David H. Hunter (RNSH: Royal North Shore Hospital)H-Index: 184
view all 4 authors...
4 CitationsSource
#1Rafael Calvo (Universidad del Desarrollo)H-Index: 11
#2Maximiliano Espinosa (Universidad del Desarrollo)H-Index: 4
Last.Paulette Conget (Universidad del Desarrollo)H-Index: 23
view all 5 authors...
Source
#1Carrie K. Hui Mingalone (Tufts University)H-Index: 3
#2Zhongbo Liu (Tufts University)H-Index: 5
Last.Li Zeng (Tufts University)H-Index: 10
view all 11 authors...
4 CitationsSource
#1Yelena Petrosyan (U of T: University of Toronto)H-Index: 5
#2Yeva Sahakyan (U of T: University of Toronto)H-Index: 3
Last.Walter P. Wodchis (U of T: University of Toronto)H-Index: 35
view all 6 authors...
1 CitationsSource
#1Bryan J. Heard (U of C: University of Calgary)H-Index: 13
#2Jillian E. Beveridge (U of C: University of Calgary)H-Index: 7
Last.Nigel G. Shrive (U of C: University of Calgary)H-Index: 41
view all 8 authors...
2 CitationsSource
#1Ari Lee (Catholic University of Korea)
#2Jong-Eun Lee (Catholic University of Korea)H-Index: 4
Source
#1Jorge L. Escobar Ivirico (University of Connecticut Health Center)H-Index: 3
#2Maumita Bhattacharjee (University of Connecticut Health Center)H-Index: 2
Last.Cato T. LaurencinH-Index: 74
view all 5 authors...
8 CitationsSource
#1Feng Xie (McMaster University)H-Index: 28
#2Bruno Kovic (McMaster University)H-Index: 4
Last.Camila Silvestre (McMaster University)H-Index: 2
view all 6 authors...
33 CitationsSource
#1Jean-Hugues Salmon (URCA: University of Reims Champagne-Ardenne)H-Index: 3
#2Anne-Christine Rat (Paris V: Paris Descartes University)H-Index: 18
Last.Bruno Fautrel (UPMC: Pierre-and-Marie-Curie University)H-Index: 25
view all 8 authors...
33 CitationsSource
4 CitationsSource
View next paperEstimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II.