Liver inflammation abrogates immunological tolerance induced by Kupffer cells.
Abstract
The liver is essential for inducing immunological tolerance toward harmless antigens to maintain immune system homeostasis. However, the precise cellular mechanisms of tolerance induction against particle-bound antigens, the role of the local hepatic microenvironment, and implications for therapeutic targets in immune-mediated diseases are currently unclear. In order to elucidate cellular mechanisms of tolerance induction in healthy and injured...
Paper Details
Title
Liver inflammation abrogates immunological tolerance induced by Kupffer cells.
Published Date
Jul 1, 2015
Journal
Volume
62
Issue
1
Pages
279 - 291
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Notes
History