Beyond TGFβ: roles of other TGFβ superfamily members in cancer

Volume: 13, Issue: 5, Pages: 328 - 341
Published: May 1, 2013
Abstract
Much of the focus on the transforming growth factor-β (TGFβ) superfamily in cancer has revolved around the TGFβ ligands themselves. However, it is now becoming apparent that deregulated signalling by many of the other superfamily members also has crucial roles in both the development of tumours and metastasis. Furthermore, these signalling pathways are emerging as plausible therapeutic targets. Their roles in tumorigenesis frequently reflect...
Paper Details
Title
Beyond TGFβ: roles of other TGFβ superfamily members in cancer
Published Date
May 1, 2013
Volume
13
Issue
5
Pages
328 - 341
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