In reply—Fructose as a Driver of Diabetes: An Incomplete View of the Evidence

We appreciate the response to our article from Dr Sievenpiper and colleagues, who argue that the highest-level evidence fails to implicate fructose as an independent driver of type 2 diabetes. We respectfully counter that the meta-analyses and systematic reviews the authors present may be misleading and that the totality of data supports our original contention. As a bottom line, Sievenpiper et al dismiss attributed harms of fructose as the...