Systematic investigation of protein phase behavior with a microfluidic formulator

Volume: 101, Issue: 40, Pages: 14431 - 14436
Published: Oct 5, 2004
Abstract
We demonstrated a microfluidic device for rapidly generating complex mixtures of 32 stock reagents in a 5-nl reactor. This null chip is fully automated and allows thousands of experiments to be performed in a single day with minimal reagent consumption. It was applied to systematically study the phase behavior of the protein xylanase over a large and complex chemical space. For each chemical formulation that demonstrated a pronounced effect on...
Paper Details
Title
Systematic investigation of protein phase behavior with a microfluidic formulator
Published Date
Oct 5, 2004
Volume
101
Issue
40
Pages
14431 - 14436
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