CRISPR-based screening of genomic island excision events in bacteria

Volume: 112, Issue: 26, Pages: 8076 - 8081
Published: Jun 30, 2015
Abstract
Genomic analysis of Streptococcus thermophilus revealed that mobile genetic elements (MGEs) likely contributed to gene acquisition and loss during evolutionary adaptation to milk. Clustered regularly interspaced short palindromic repeats-CRISPR-associated genes (CRISPR-Cas), the adaptive immune system in bacteria, limits genetic diversity by targeting MGEs including bacteriophages, transposons, and plasmids. CRISPR-Cas systems are widespread in...
Paper Details
Title
CRISPR-based screening of genomic island excision events in bacteria
Published Date
Jun 30, 2015
Volume
112
Issue
26
Pages
8076 - 8081
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